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Scientists develop high-sensitivity software for searching massive DNA databases

April 01, 12:44 UTC+3 MOSCOW
Nucleotide Similarity Scanner outperforms industry standard tools in combined sensitivity, accuracy and speed
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© Evgeniy Kurskov/ITAR-TASS, archive

MOSCOW, April 1. /TASS /. A new computer program was designed by Russian and American scientists and specialized for searching massive DNA databases for distant similarities, reports Institute for information transmission problems of the Russian Academy of Sciences (IITP RAS) press-service. Anna Kaznadzey, a junior researcher at IITP RAS took part in this work.

"Its targeted applications include phylogenomics, comparative and functional studies of non-coding sequences, contamination detection, etc. NSimScan [Nucleotide Similarity Scanner] outperforms industry standard tools in combined sensitivity, accuracy and speed," Kaznadzey said.

NSimScan is available at github. Software description is published in Bioinformatics journal by Oxford University Press. It is implemented in C++, distributed under MIT license and supported on Linux, OS X and Windows.

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